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ÀÏȸ¿ë ¾à¹°ÁÖÀÔ±â·Î °¡Á¤¿¡¼­ Ç×¾ÏÄ¡·á ÁßÀÎ ´ëÀå¾Ï ȯÀÚÀÇ »îÀÇ Áú

Quality of Life in Colorectal Cancer Patients at Home 5-Fluorouracil Chemotherapy with Disposable Elastomeric Infusion Pumps

ÀÓ»ó°£È£¿¬±¸ 2022³â 28±Ç 1È£ p.76 ~ 87
KMID : 1004620220280010076
ÀÌÃæÀº ( Lee Chung-Eun ) - Severance Hospital Division of Nursing

±è³ª¿µ ( Kim Na-Young ) - Severance Hospital Division of Nursing
¹Ú¹ÌÈñ ( Park Me-Hee ) - Severance Hospital Division of Nursing
ÀÌÀ±Á¤ ( Lee Yoon-Jung ) - Severance Hospital Division of Nursing
±èÁø¶ó ( Kim Jin-Ra ) - Severance Hospital Division of Nursing
¹é¹ÎÁÖ ( Baek Min-Ju ) - Severance Hospital Division of Nursing
±èÈ¿Áø ( Kim Hyo-Jin ) - Severance Hospital Division of Nursing
º¯Àº¼º ( Byun Eun-Sung ) - Severance Hospital Division of Nursing
±æÀ±°æ ( Kil Yun-Kyung ) - Severance Hospital Division of Nursing
±èÈñÁ¤ ( Kim Hee-Jung ) - Yonsei University College of Nursing Mo-Im Kim Nursing Research Institute

Abstract

¸ñÀû: º» ¿¬±¸´Â ÀÏȸ¿ë ¾à¹°ÁÖÀԱ⸦ ÀÌ¿ëÇÏ¿© °¡Á¤¿¡¼­ Ç×¾ÏÄ¡·á ÁßÀÎ ´ëÀå¾Ï ȯÀÚÀÇ »îÀÇ Áú¿¡ ¿µÇâÀ» ¹ÌÄ¡´Â ¿äÀÎÀ» È®ÀÎÇϱâ À§ÇØ ½ÃÇàµÇ¾ú´Ù.

¹æ¹ý: 2019³â 9¿ùºÎÅÍ 2021³â 1¿ù±îÁö ÃÑ 179¸í ´ëÀå¾Ï ȯÀÚµéÀ» ´ë»óÀ¸·Î Á¶»çÇÏ¿´´Ù. ÀϹÝÀû ÀÚ±âÈ¿´É°¨, ±¹¸³¾Ï¼¾ÅÍ ½É¸®Áõ»óÆò°¡Áö, EORTC QLQ-C30¸¦ »ç¿ëÇÏ¿´°í, µ¶¸³Ç¥º» t°ËÁ¤, ÀÏ¿øºÐ»êºÐ¼®, À§°èÀû ȸ±ÍºÐ¼®À» ½Ç½ÃÇÏ¿´´Ù.

°á°ú: ´ëÀå¾Ï ȯÀÚÀÇ 52.0%°¡ ½É¸®Àû µð½ºÆ®·¹½º¸¦ °æÇèÇÏ°í ÀÖ´Â °ÍÀ¸·Î ³ªÅ¸³µ´Ù. º» ¿¬±¸ °á°ú ½É¸®Àû µð½ºÆ®·¹½º À¯¹«(¥â=-.20, p=.005), Ç×¾ÏÄ¡·á Â÷¼ö(¥â=.19, p=.002), ½Ä¿åºÎÁø(¥â=-.20, p=.001), ÇÇ·Î(¥â=-.16, p=.035), ½Åü±â´É(¥â=-.16, p=.024) ¹× Á¤¼­±â´É(¥â=-.15, p=.025)ÀÌ ´ëÀå¾Ï ȯÀÚÀÇ »îÀÇ Áú¿¡ °ü·ÃÀÌ ÀÖÀ¸¸ç, ¼³¸í·ÂÀº 45.0%À̾ú´Ù.

°á·Ð: °¡Á¤¿¡¼­ ÀÏȸ¿ë ¾à¹°ÁÖÀÔ±â·Î óÀ½ Ä¡·á¸¦ ½ÃÀÛÇϰųª, Ç×¾ÏÄ¡·á ÈÄ Àç¹ßµÇ¾î ¾àÀ» ¹Ù²ã¼­ ´Ù½Ã Ç×¾ÏÄ¡·á¸¦ ½ÃÀÛÇÏ´Â °æ¿ì °¡Á¤¿¡¼­ ÀÏ»ó»ýÈ°¿¡ °Þ´Â ¹®Á¦¿¡ Àß ÀûÀÀÇÒ ¼ö ÀÖµµ·Ï ½É¸®Àû µð½ºÆ®·¹½º¸¦ ³·Ãß°í ½Åü ¹× Á¤¼­ ±â´ÉÀ» ÁõÁø½ÃÅ°µµ·Ï ÁöÁöÇÏ´Â °³º°È­µÈ °£È£ÁßÀ縦 Á¦°øÇØ¾ß ÇÒ °ÍÀ¸·Î »ý°¢µÈ´Ù. ÀÓ»óÀûÀ¸·Î ÀÇ¹Ì ÀÖ´Â Àý´ÜÁ¡À» ÀÌ¿ëÇÏ¿© °íÀ§Ç豺À» Á¶±â ¼±º°°Ë»ç¿¡ È°¿ëÇÒ °ÍÀ» ±â´ëÇÏ´Â ¹ÙÀÌ´Ù.

Purpose: The purpose of this study was to examine the psychological distress related to quality of life (QoL) of patients with colorectal cancer receiving 5-fluorouracil (5-FU) chemotherapy at home with disposableElastomeric infusion pumps.
Methods: In this study, 179 colorectal outpatients were recruited between September 2019 and January 2021. National Cancer Center Psychological Symptom Inventory scores, generalself-efficacy, and the EORTC QLQ-C30 scores were measured. Data were analyzed using Independent t-test, One-way ANOVA with Bonferroni post hoc analysis, and hierarchical multiple linear regression with the SPSS/WIN 26.0 programs.

Results: The overall prevalence of psychological distress was 52.0% in colorectal patients. In multiple regression, psychological distress (¥â=-.20, p=.005), appetite loss (¥â=-.20, p=.001), chemotherapy cycles (¥â= .19, p=.002), fatigue (¥â=-.16, p=.035), physical functioning (¥â=-.16, p=.024), and emotional functioning (¥â=-.15, p=.025) were significant factors of QoL, and the final model explained 45.0% of the total variance of QoL.

Conclusion: Supporting patients toward decreased psychological distress and increased physical and emotional functioning, especially in the first or second cycle of chemotherapy, could be used to improve their QoL. To consider the thresholds for clinical importance, it is necessary to increase the interpretation of psychological distress in clinical practice and further research.
KeyWords
µð½ºÆ®·¹½º, »îÀÇ Áú, ¿Ü·¡ Ç×¾Ï, ´ëÀå¾Ï
Distress, Quality of Life, Chemotherapy, Colorectal Cancer
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ÇмúÁøÈïÀç´Ü(KCI)